You can take as much of this stuff as you want, any time of day, but the recommended amount is 1 spoonful in water several times a day between meals. Let the bitter taste sit on your tongue a bit. The bitter receptors on the back of your tongue become activated, which stimulates the vagus nerve that leads directly to the liver, causing it to flush. The bitter taste is not fun, but that’s what activates the liver. I personally love this formula. I use it a lot. Yes, you can take along with Parasite Formula. Do not take while pregnant.